4178 SES, MC 111
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Research in the Mankad group focuses on understanding multimetallic cooperativity in catalysis. We approach this through two parallel approaches. First, we invent new bimetallic complexes designed to catalyze transformations of importance to organic synthesis as well as small-molecule conversions of relevance to energy storage and environmental remediation. In some cases, the bimetallic cooperativity inherent to these bimetallic complexes has allowed us to use earth-abundant metals for catalytic transformations typically associated with single-site precious metal systems. In other cases, completely novel reactivity has emerged through careful study of the cooperative effect. Secondly, we construct synthetic complexes that model the active sites of metalloproteins that feature bioinorganic clusters thought to utilize multimetallic cooperativity in nature. The goal is to understand how nature has evolved to use multimetallic cooperativity to mediate multielectron redox transformations, and to apply those lessons to the design of new synthetic catalysts. Students and postdoctoral researchers use techniques for air-free chemical manipulation, and methods of analysis in use include multinuclear NMR spectroscopy, IR spectroscopy, single-crystal X-ray crystallography, mass spectrometry, cyclic voltammetry, and quantum chemical calculations. For more information, please visit our group webpage.
- Mazzacano, T. J.; Mankad, N. P. “Thermal C-H borylation using a CO-free iron boryl complex.” Chem. Commun. 2015, 51, 5379-5382.
- Banerjee, S.; Karunananda, M. K.; Bagherzadeh, S.; Jayarathne, U.; Parmelee, S. R.; Waldhart, G. W.; Mankad, N. P. “Synthesis and Characterization of Heterobimetallic Complexes with Direct Cu–M Bonds (M = Cr, Mn, Co, Mo, Ru, W) Supported by N-Heterocyclic Carbene Ligands: A Toolkit for Catalytic Reaction Discovery.” Inorg. Chem. 2014, 53(20), 11307-11315.
- Johnson, B. J.; Lindeman, S. V.; Mankad, N. P. “Assembly, Structure, and Reactivity of Cu4S and Cu3S Models for the Nitrous Oxide Reductase Active Site, CuZ*.” Inorg. Chem. 2014, 53(19), 10611-10619.
- Mazzacano, T. J.; Mankad, N. P. “Base Metal Catalysts for Photochemical C-H Borylation That Utilize Metal-Metal Cooperativity.” J. Am. Chem. Soc. 2013, 135(46), 17258-17261.
S.B., Massachusetts Institute of Technology (Advisor: Joseph Sadighi), 2000-2004.
Ph.D., California Institute of Technology (Advisor: Jonas Peters), 2004-2009.
NIH Ruth L. Kirschstein NRSA Postdoctoral Fellow, University of California at Berkeley (Advisor: Dean Toste), 2010-2012.