Dr. Mike Stieff’s lab conducts research on spatial thinking in chemistry and the design of visualizations for supporting chemistry learning. With funding from the U.S. Department of Education, he has developed The Connected Chemistry Curriculum, a self-contained high school curriculum, which teaches chemistry using computer visualizations. Currently, the curriculum is employed by teachers throughout the United States, South Africa, Germany, Brazil, and Argentina. His work on spatial thinking in chemistry has yielded critical insights into scientific problem solving strategies and alternative pedagogies for teaching spatial problem solving in undergraduate chemistry. Importantly, this work has revealed that men and women apply different strategies for spatial problem solving in science and that alternative instructional approaches differentially impact the performance of men and women in the classroom. Additionally, Stieff’s lab makes use of eye-tracking and head-tracking technologies to support spatial reasoning and chemistry learning and is currently exploring new interface designs that allow learners to embodied spatial relationships embedded in scientific models.