Chemistry Undergraduate Awards Day with Keynote Speaker Dr. Irida Kastrati, UIC Department of Physiology and Biophysics
May 2, 2018
5:00 PM - 7:00 PM
Targeting Inflammation to Eradicate Cancer Stem Cells for Breast Cancer Therapy.
By Irida Kastrati, Ph.D.
Therapy options for aggressive cancers (i.e., advanced stage, recurrent, or metastatic) are limited; this translates to poor patient outcome and results in over 40,000 deaths each year. Clearly there is an urgent need for improved therapeutics to manage aggressive disease in the clinic. Cancer stem cells (CSCs) are a subset of cells within the tumor that are resistant to conventional therapies, tumor initiating, metastatic, and responsible for tumor recurrence. Therefore, targeting breast CSC promises to sensitize to therapy even resistant, aggressive tumors, and prevent future recurrence and metastasis. However, to develop new therapies against CSCs, it is essential to understand factors and pathways that drive their survival and propagation. Our efforts at both elucidating the underlying factors and therapeutically targeting breast CSC will be discussed.
Date posted
Oct 24, 2019
Date updated
Oct 24, 2019