Recent Faculty Accomplishments!
Two of our faculty have reported substantial new findings in several publications.
Prof. Stephanie Cologna recently published "Mass Spectrometry Imaging of Lipids: Generation of Untargeted Consensus Spectra Reveals Spatial Distributions in Niemann-Pick Disease, Type C1" in the Journal of Lipid Research. Shown above is an example of their use of mass spectrometry imaging to map lipid distribution in a neurodegenerative disease model.
Talk about retirement? Not to our emeritus Prof. Timothy Keiderling, who published 8 papers in 2018! These include:
1. "Mini review: Instrumentation for vibrational circular dichroism spectroscopy, still a role for dispersive instruments" Timothy A. Keiderling and Ahmed Lakhani, Chirality, 30, 238-253 (2018) doi: 10.1002/chir.22799.
2. "Role of Aromatic Crosslinks in Structure and Dynamics of Model Three-stranded β-Sheet Peptides" Scheerer, David; Chi, Heng; McElheny, Dan; Samer, Ayesha; Keiderling, Timothy; Hauser, Karin, Journal of Physical Chemistry A, 122, 543-553 (2018) DOI: 10.1021/acs.jpca.7b10190.
3. "Theory of Molecular Vibrational Zeeman Effects as Measured with Circular Dichroism” Timothy A. Keiderling and Petr Bouř, Physical Review Letters, 121, 073201 (2018) doi: 10.1103/PhysRevLett.121.073201.
4. "Vibrational Circular Dichroism Sheds New Light on the Competitive Effects of Crowding and β‑Synuclein on the Fibrillation Process of α‑Synuclein" Evelien Van de Vondel, Pieter Baatsen, Roos Van Elzen, Anne-Marie Lambeir, Timothy A. Keiderling, Wouter Herrebout, Christian Johannessen, Biochemistry, 57, 5989−5995 (2018). doi:10.1021/acs.biochem.8b00780.
5. Feature Paper: "Focused review: Instrumentation for vibrational circular dichroism spectroscopy, Method comparison and newer developments," Timothy A. Keiderling, Molecules (MDPI), 23, 2404 (2018) doi:10.3390/molecules23092404.
6. "Isotopically Site-Selected Dynamics of a Three-Stranded β-Sheet Peptide Detected with Temperature-Jump IR-Spectroscopy" David Scheerer, Heng Chi, Dan McElheny, Timothy A. Keiderling, Karin Hauser, Journal of Physical Chemistry, 122, 10445-10454 (2018). doi: 10.1021/acs.jpcb.8b08336.
7. "Vibrational Coupling of Small Molecules with Potential Applications to Determination of Polymer Structures" Allen Walker, Timothy A. Keiderling and Ahmed Lakhani, Chemical Educator, 23, 253–260 (2018) foi:10.1333/s00897182831a.
8. "β2-Type amyloid-like fibrils of poly-L-glutamic acid convert into long uninterrupted helices upon dissolution in dimethyl sulfoxide" Sylwia Berbeć, Robert Dec, Dmitry Molodenskiy, Beata Wielgus-Kutrowska, Christian Johannessen, Agnieszka Hernik-Magoń, Fernando Tobias, Agnieszka Bzowska, Grzegorz Ścibisz, Timothy A. Keiderling, Dmitri Svergun, Wojciech Dzwolak, Journal of Physical Chemistry, 122, 11895-11905 (2018). doi:10.1021/acs.jpcb.8b08308.
Prof. Keiderling also published an Encyclopedia entry:
9. “Quantum mechanical simulations of biopolymer vibrational spectra”, 10 pp, and “Vibrational Circular Dichroism of Biopolymers”, 8 pp, Timothy A. Keiderling,Encyclopedia of Biophysics– revision of two entries, ed. Gordon Roberts, (Vibrational Spectroscopy section ed. Andreas Barth), Springer, EBSA, European Biophysical Societies Association (2018). doi:10.1007/978-3-642-35943-9_107-1 and doi:10.1007/978-3-642-35943-9_125-1.