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Photo of Papadantonakis, George A.

George A. Papadantonakis

Clinical Associate Professor; Director of General Chemistry; Assistant Head, and interim Director of Undergraduate Studies



4506 SES, MC 111

Office Phone:

(312) 996-2790


George Papadantonakis focuses on cancer biophysics. Using ab initio quantum mechanical calculations, we investigate the energetics of DNA damage induced by ultraviolet radiation and methylation. Nucleotide ionization energies provide a quantitative measurement of the electron-donating properties of DNA. Attack of DNA by methylation agents plays a ubiquitous role in mechanisms of chemical carcinogenesis and cancer chemotherapy.